Tag: medicinal chemistry

Questions Related to medicinal chemistry

Which of these was the largest selling antacid?

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. Cimetidine

  2. Zantac

  3. Sulpha

  4. none of these

Show answer
Correct Option: A
Explanation:

Cimetidine (also called Tegamet) was the largest selling antacid.
It prevent the interaction between histamine and the receptors in the stomach wall, releasing less amount of acid.

Which of the following is an antacid?

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. Sodium bicarbonate

  2. Magnesium hydroxide

  3. Magnesium carbonate

  4. All of the above

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Correct Option: D
Explanation:

Examples of antacid include sodium bicarbonate, magnesium hydroxide, magnesium carbonate and aluminium hydroxide, as they are all basic in nature.

Most commonly used antacids are:

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. weak bases

  2. strong bases

  3. weak acids

  4. strong acids

Show answer
Correct Option: A
Explanation:


Most commonly used antacids are weak bases.
Examples of antacid includes sodium bicarbonate, magnesium hydroxide, magnesium carbonate and aluminium hydroxide. An antacid is the substance which neutralizes the acid and raise the pH to an appropriate level in stomach. They should not be caustic like strong bases.

What is an antacid?

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. The substance which neutralizes the acid and raises the pH to an appropriate level in stomach.

  2. The substance which neutralizes the acid and lowers the pH to an appropriate level in stomach.

  3. The substance which neutralizes the base and raises the pH to an appropriate level in stomach.

  4. none of these

Show answer
Correct Option: A
Explanation:

An antacid is the substance which neutralizes the acid and raises the pH to an appropriate level in stomach. In other words, antacid is a base which neutralizes excess of acid in the stomach. Examples of antacid include sodium bicarbonate, magnesium hydroxide and aluminium hydroxide. They control the symptoms and not the cause.

Which of the following cannot be used as an antacid?

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. Rantidine

  2. Cimetidine

  3. Metal hydroxides

  4. None of the above

Show answer
Correct Option: D
Explanation:

Antacid is a drug (or medicine) preventing or correcting acidity, especially in the stomach.
To neutralize the acid in stomach, antacid should be basic in nature.
All three can be used as antacids since they are basic in nature.

The main function of an antacid is:

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. to neutralize body acid.

  2. to neutralize body base.

  3. both a and b

  4. none of these

Show answer
Correct Option: A
Explanation:

Antacid is a chemical substance which removes excess acid and raises the pH to an appropriate level in stomach, preventing heatburn and upset stomach,

Name the new antacid which prevents formation of acid in stomach.

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. Omeprazole

  2. Pantaprazole

  3. Hemoprazole

  4. none of these

Show answer
Correct Option: A
Explanation:

Omeprazole is the recently developed antacid which is used to prevent the formation of acid in the stomach.

Which of the following substance is an antacid?

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. $NaCl$

  2. $Mg(OH) _2$

  3. $HCl$

  4. $H _2SO _4$

Show answer
Correct Option: B
Explanation:
Due to its mildly basic and non-toxic nature, magnesium hydroxide is widely used as an antacid to neutralize stomach acids and prevent indigestion and heartburn. 

It is also used as a laxative, antiperspirant, underarm deodorant, to treat sores, in wastewater treatment, and as a fire retardant.

Therefore, the correct option is B.

Which of the following is not used as an antacid ? 

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. Magnesium hydroxide

  2. Sodium carbonate

  3. Sodium bicarbonate

  4. Aluminium phosphate

Show answer
Correct Option: D
Explanation:

An antacid is a substance which neutralizes stomach acidity and is used to relieve heartburn, indigestion or an upset stomach.

Example- $Mg(OH) _2, Na _2CO _3, NaHCO _3$.
Aluminum phosphate is not used as an antacid.
Hence, the correct option is D.

Which of the following anti histamine does not act as antacid?

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. Terfendine

  2. Lansoprazole

  3. Cintindine

  4. Rantidine

Show answer
Correct Option: B
Explanation:

$(B)$ Lansoprazole

It does not act as antacid because it is used for treatment of nonerosive gastroesophsgeal reflux disease.