Tag: amphibolic pathway

Questions Related to amphibolic pathway

The site of Krebs cycle is

  1. Cytoplasm

  2. Mitochondrial matrix

  3. Intermembrane space of mitochondria

  4. Racker's particles


Correct Option: B

In Kreb's cycle formation of ___________________.

  1. $34$ ATP takes place

  2. $38$ ATP takes place

  3. $15$ ATP from each acetyl Co-A takes place

  4. $12$ ATP from each acetyl Co-A takes place $(24\ ATP)$


Correct Option: A

How many oxidation step take place during glycolysis, link reaction and Kreb's cycle.

  1. $1, 1 and 1$

  2. $1, 1 and 4$

  3. $1, 1 and 3$

  4. $1, 1 and 8$


Correct Option: B
Respiratory Pathway is _______.
  1. Catabolic

  2. Amphibolic

  3. Anabolic

  4. Endergonic


Correct Option: B
Explanation:

The same respiratory process which acts as a catabolic pathway for respiratory substrates also acts as an anabolic pathway for the synthesis of various intermediary metabolic products and secondary metabolites. The respiratory pathway, therefore, acts both as catabolic as well as an anabolic pathway. Thus, it is better to call it the amphibolic pathway rather than a catabolic pathway alone.

So the correct option is B.

During amphibolic pathway, acetyl Co-A can perform the biosynthesis of 

  1. Amino acid

  2. Gibberellic acid

  3. Fatty acid

  4. All of the above


Correct Option: C
Explanation:

Fatty acid synthesis takes place in the cytoplasm of the cell. It is the creation of fatty acids from acetyl-CoA and NADPH through the action of enzymes called fatty acid synthases. Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the glycolytic pathway. 

So, the correct option is 'Fatty acid'.

Find the incorrect match (with respect to ATP gain) -

  1. Bacterial cell - $38$ ATP or $2$ ATp

  2. Citric Acid Cycle - $12$ ATP

  3. Nerve cell - $38$ ATP

  4. Liver cell - $38$ ATP


Correct Option: A
Explanation:

The Kreb’s Cycle gives 3 moles of NADH1 mole of FADH and 1 mole of ATP per cycle of substrate i.e per 1 mole of Acetyl CoA. However net ATP i.e after ETS which would make the answer to 12 ATP(9+2+1) respectively.

36 ATPs are produced in Aerobic Respiration involving the complete breakdown of glucose molecule into carbon-dioxide and water using oxygen as final electron aceptor

Complete oxidation of glucose molecule takes place in 3 sequential reactions -

1.Glycolysis occuring in cytoplasm

2.Kreb cycle occuring in mitochondrial matrix

3 Electron transport chain (ETC )and oxidative phosphorylation occuring in inner mitochondrial membrane . So,total number of ATPs produced in aerobic respiration are

Glycolysis - 6/8 ATPs

Link reaction and kreb cycle - 30ATPs

Total -36/38 ATPs.


So, the correct option is 'Option A'.

Which of the following steps of respiration is amphibolic?
  1. Glycolysis

  2. Oxidative decarboxylation of pyruvate

  3. TCA cycle

  4. Oxidative phosphorylation


Correct Option: C
Explanation:

TCA or Krebs' cycle is amphibolic (both catabolic and anabolic) because it provides a number of intermediates for anabolic pathways.

Mechanism of aerobic respiration was discovered by

  1. Kreb

  2. Calvin

  3. Hatch and Slack

  4. Pasteur


Correct Option: A
Explanation:

Mechanism of aerobic respiration was given by Kreb. Thus it was named as Krebs cycle. Aerobic respiration is the respiration, which involves the breakdown of the substrate in the presence of oxygen (oxidation process).

Which one of the following reactions is an example of oxidative decarboxylation?

  1. Conversion of succinate to fumarate.

  2. Conversion of fumarate to malate.

  3. Conversion of pyruvate to acetyl Co-A.

  4. Conversion of citrate to isocitrate.


Correct Option: C
Explanation:

The conversion of pyruvate to acetyl-CoA is a linker step between glycolysis and Krebs cycle. After the entry of pyruvate in the mitochondria the acetylation takes place in the perimitochondrial space which is the space between the inner and outer mitochondrial membrane. Each molecule of pyruvic acid is oxidatively decarboxylated to acetyl coA by the action of an enzyme complex pyruvate dehydrogenase. The acetyl coA then enters the Krebs cycle.  Thus the correct answer is option C.

The importance of the Kreb's cycle is 

  1. Production of amino acid

  2. Production of vitamin

  3. Production of ATP molecule through oxidative phosphorylation

  4. ATP formation through oxidative and substrate level phosphorylation


Correct Option: D
Explanation:

The pyruvic acid enters Krebs cycle in form of acetyl CoA where it is oxidatively decarboxylated into CO$ _2$. The complete Kreb cycle leads to the net formation of 2 molecules of ATP by substrate-level phosphorylation, 8 molecules of NADH plus 2 molecules of FADH$ _2$ (via succinate dehydrogenase). The NADH and FADH$ _2$ then enter the ETS to drive ATP production by substrate level phosphorylation. 

So, the correct answer is option D.