Tag: glucose metabolism

Questions Related to glucose metabolism

How many ${ CO } _{ 2 }$ molecules are produced from one pyruvate on complete oxidation :-

  1. 1

  2. 2

  3. 3

  4. 4


Correct Option: B
Explanation:

During the complete oxidation of pyruvate, two carbon atoms are lost in the form of CO2 - one during the conversion of isocitrate to alpha-ketoglutarate and the second during the conversion of alpha-ketoglutarate to succinyl CoA.
So, the correct answer is '2'.

Sequence of aerobic metabolic breakdown of glucose is

  1. Glycolysis-transition-citric acid cycle-electron transport system

  2. Transition-glycolysis-electron transport-citric acid cycle

  3. Electron transport system-citric acid cycle- transition-glycolysis

  4. None of the above


Correct Option: A
Explanation:

  • For the aerobic respiration the substrate glucose has  to undergo a following set of process 
  • First of which is glycolysis where the molecule of glucose is broken down to 2 molecules of pyruvate.
  • These pyruvate molecules are to be cconverted to Acetyl CoA so that it can enter the mitochondrial membrane and undergo kerb cycle.
  • After being converted to acetyl coA it takes part in kerb cycle where molecules of NADH, FADH and ATP are formed.
  • These NADH, FADH molecules are the electron acceptors which are used in ETS to transport electron and hydrogen ions through the complexs.
  • These electrons and hydrogen ions are used for the formation of ATP via ATP synthase.
  • Therefore the process for the aerobic breakdown of glucose is Glycolysis followed by transition of pyruvate then citric acid cycle which is followed by electron transport system.
  • Therefore the correct answer is 'Glycolysis-transition-citric acid cycle-electron transport system'








How many oxygen atoms are required for the complete oxidation of one molecule of pyruvate?

  1. 2

  2. 5

  3. 4

  4. 3


Correct Option: A
Explanation:

Under Anaerobic conditions, Pyruvic Acid enters in matrix of mitochondrion and undergoes oxidative decarboxylation to form 2 carbon energy rich compound called Acetyl Co A.

This process utilizes 2 oxygen atoms. Incomplete oxidation of Pyruvate leads to the formation of lactic acid in muscles and formation of ethyl alcohol in yeast as a process of fermentation.

So, the correct answer is '2'

The receptors for opioids are present in?

  1. Gastrointestinal tract

  2. CNS

  3. Circulatory and respiratory systems

  4. Both $(1)$ & $(2)$


Correct Option: D
Explanation:

Opioids are a type of drug. They are also referred to as narcotics. In the human body, the opioid receptors are present at a variety of locations, including the brain, in the spinal cord, on peripheral neurons, and the digestive tract. They often act as pain relievers.

So, the correct answer is 'Both (1) & (2)'.
(1(2)'.

How many molecules of NADH are produced when four molecules of phosphoglyceraldehde are converted into four molecules of pyruvate?

  1. $2$

  2. $6$

  3. $8$

  4. $4$


Correct Option: A
Explanation:

Glycolysis is a series of reactions that extract energy from glucose by splitting it into two three-carbon molecules called pyruvates. Glycolysis takes place in the cytosol of a cell, and it can be broken down into two main phases: the energy-requiring phase and  the energy-releasing phase. Each three-carbon sugar is converted into another three-carbon molecule, pyruvate, through a series of reactions. In these reactions, ATP molecules and one NADH molecule are made. Because this phase takes place twice, once for each of the two three-carbon sugars, it makes four ATP and two NADH overall.

So the correct option is '2'.

During glycolysis the number of ATP molecules utilized to change glucose into fructose 1, 6 diphosphate are

  1. 4

  2. 3

  3. 2

  4. 1


Correct Option: C
Explanation:

2 molecules of ATP is utilized during the conversion of glucose into fructose 1,6 diphosphate.

So the correct option is '2'.

Substrate -level phosphorylation accounts for approximately what percentage of the ATP formed by the reactions of glycolysis?

  1. $0\%$

  2. $2\%$

  3. $10\%$

  4. $100\%$


Correct Option: D
Explanation:

Substrate-level phosphorylation is the direct transfer of phosphate group to ADP to form ATP. It accounts of 100% of the ATP formed by the reactions of glycolysis. The first substrate-level phosphorylation occurs when 1, 3 - diphosphoglyceraldehyde is converted to 1, 3 - diphosphoglyceric acid and 2 NADH$ _2$ are formed, that is 6 ATP are formed. The 1, 3-diphosphoglyceric acid is then dephosphorylated to 3 phosphoglyceric acid producing 2 ATP via substrate-level phosphorylation. The second substrate-level phosphorylation occurs when phosphoenolpyruvic acid is converted to pyruvic acid producing 2 ATP molecules.

Thus, the correct answer is option D. 

Which hormone secreted by thyroid gland ?

  1. Thyroxine

  2. Adrenalin

  3. Testosterone

  4. Phyrotrophic


Correct Option: A
Explanation:
  • The thyroid gland is composed of two lobes that are located on either side of the trachea.
  • Follicular cells of the thyroid gland synthesize two hormones, tetraiodothyronine or thyroxine ($T _4$) and triiodothyronine ($T _3$). 
  • Thyroid hormones play an important role in the regulation of the basal metabolic rate. 
  • Hence the hormone secreted by the thyroid gland is thyroxine.
  • So, the correct answer is 'Thyroxine'.

Glycogenolysis is

  1. Oxidation of sugar

  2. Conversion of glycogen into glucose

  3. Conversion of glucose into glycogen

  4. Conversion of glycogen into fat


Correct Option: B

Glycogenolysis occurs in.

  1. Muscles

  2. Liver

  3. Kidney

  4. Small intestine


Correct Option: B