Tag: gene therapy

Questions Related to gene therapy

An abnormal gene is replaced by normal gene. It is called __________.

zoology applications of biotechnology gene therapy application of biology in therapy and vaccine gene cloning

  1. Gene therapy

  2. Cloning

  3. Mutation

  4. None of the above

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Correct Option: A

Immune deficiency disorder, which occur due to mutation in gene, involved in maturation of T and B lymphocytes is

zoology applications of biotechnology gene therapy application of biology in therapy and vaccine gene cloning

  1. IDDM

  2. Hashimoto disease

  3. SCID

  4. Pernicious anemia

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Correct Option: C
Explanation:

  • Insulin-Dependent Diabetes Mellitus or IDDM is an immune deficiency disorder. It occurs due to a mutation in a gene involved in insulin-producing β cells in the pancreas. 
  • Hashimoto's disease is an autoimmune disorder that results in hypothyroidism. It results in defects in the maturation of T lymphocytes. 
  • Severe combined immunodeficiency (SCID) is an immunodeficiency syndrome. It occurs due to a mutation in the gene involved in the maturation of T and B lymphocytes. 
  • Pernicious anemia is also called as vitamin B$ _{12}$ deficiency syndrome. It results due to a lack of intrinsic factor. 
Thus, the correct answer is 'Hashimoto disease and SCID.'

"Introduction of a normal functional gene into cells, in order to replace defective or mutated gene'." is known as 

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  1. Biosafety

  2. Biopiracy

  3. Biopatent

  4. Gene therapy

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Correct Option: D
Explanation:

Introduction of a normal functional gene into cells, in order to replace defective or mutated gene is known as gene therapy. It is also called as gene transfer. It is done to correct genetic disorders. Biosafety is the prevention of large-scale loss of biological integrity. Biopiracy is the practice of exploiting indigenous knowledge of nature, originating with indigenous peoples without compensation to the indigenous people. Biopatent is a patent granted by the government to the inventor of biological entities.

Thus, the correct answer is 'Gene therapy.'

a functional ADAcDNA can be introduced into cells of the patients receiving gene therapy by using vector constituted by

zoology applications of biotechnology gene therapy application of biology in therapy and vaccine gene cloning

  1. E.coil

  2. Reoviridae

  3. Retrovirus

  4. Agrobacterium

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Correct Option: A
Explanation:
The deficiency of the purine salvage enzyme adenosine deaminase is associated with severe B and T-cell dysfunction. In order to investigate the ADA molecule, gene therapy using E.coli, cDNA clones encoding ADA gene sequences are obtained.
So the correct option is 'E.coli'.

Cystic fibrosis can be treated by .......... gene therapy.

zoology applications of biotechnology gene therapy application of biology in therapy and vaccine gene cloning

  1. TGP-B

  2. TPA

  3. DNase

  4. BGH

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Correct Option: C

A diabetic Patient cannot be given insulin orally but it has to be injected intravenously. These days has helped to avait injection taking.

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  1. amniocentesis

  2. genetic engineering

  3. gene therapy

  4. transgenic organism

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Correct Option: B,C