Tag: disorders of musculoskeletal system

Questions Related to disorders of musculoskeletal system

The term tetanus refers to

  1. The partial sustained contraction of major supporting muscles

  2. A stronger contraction resulting from multiple motor unit summation

  3. The result of wave summation, which produces a smooth and sustained contraction of a muscle

  4. The state of muscle fatigue caused by depletion of ATP and accumulation of lactic acid


Correct Option: C
Explanation:

  • A decline in a muscle's ability to maintain a constant level of force, or tension after prolonged, repetitive stimulation is called tetanus.
  • A tetanic contraction is a sustainable contraction evoked when motor nerve innervates a skeletal muscle emitting action potential at a very high rate.
So, the correct option is 'The result of wave summation, when produces a smooth and sustained contraction of a muscle'.

Select the correct statement regarding the specific disorder of muscular or skeletal system.

  1. Muscular dystrophy - age related shortening of muscles

  2. Osteoporosis - decrease in bone mass and higher chances of fractures with advancing age

  3. Myasthenia gravis - Autoimmune disorder which inhibits sliding of myosin filaments

  4. Gout - Inflammation of joints due to extra deposition of calcium.


Correct Option: B
Explanation:

A. Muscle dystrophy: It involves progressive degeneration of skeletal muscle due to a genetic defect.

B. Osteoporosis: It is a reduction in bone tissue mass causing weakness of skeletal strength. It leads to vertical compression or crushes fracture. It occurs in postmenopausal women and elderly men.
C, Myasthenia gravis: It is an autoimmune disorder that affects neuromuscular junction leading to fatigue, weakening and ultimately paralysis of skeletal muscle.
D. Gout: It is an inherited disorder of purine metabolism, occurring especially in men.
So, the correct answer is ' Osteoporosis- decrease in bone mass and higher chances of fractures with advancing age.

Repetitive muscular activity at moderate levels, such as weight training, can result in

  1. Denervation atrophy

  2. Mood swings

  3. Muscular hypertrophy

  4. A decline in health


Correct Option: C
Explanation:

  • Muscular dystrophy is a collection of muscle-wasting conditions. 
  • A lack of a protein called dystrophin is the main cause of muscular dystrophy.
So, the correct option is 'Muscular dystrophy'.

Symptoms of tetanus include

  1. Muscle cramps or spasms in your legs

  2. Swollen neck

  3. Bowed legs

  4. All the above


Correct Option: A
Explanation:
Tetanus is caused by the bacterium Clostridium tetani (C tetani). It is a  fatal disease of the nervous system caused by nerve toxins released by the bacterium.
Symptoms of tetanus include: 
a)Tetanus often begins with mild spasms in the jaw muscles known as lockjaw. The spasms can also affect the facial muscles and experience spasms and stiffness in various muscles, especially those in jaw, abdomen, chest, back, and neck.
b)Muscle cramps or spasms in your legs.
c)Difficulty swallowing.
d)fever, high blood pressure, nervous system dysfunction, or sweating.
Hence symptoms of tetanus include Muscle cramps or spasms in your legs.
So, the correct option is 'Muscle cramps or spasms in your legs'.

Metabolic arthritis is commonly called

  1. Rheumatism

  2. Gout

  3. Tuberculosis

  4. Cancer


Correct Option: B

Sprain involves

  1. Overstretching of ligament

  2. Overstretching of tendon

  3. Dislodging of bone

  4. Both A and B


Correct Option: A
Explanation:

A sprain is a stretching or tearing of ligaments which are the tough bands of fibrous tissue that connect two bones together in the joints. The most common causes of sprains are falling, twisting etc. These types of injuries may cause the joint to move out of its normal range of movement that causes the tearing or stretching of the ligament. So, the correct answer is 'Overstretching of ligament'.

Sprain is due to outstretching/pulling of

  1. Muscles

  2. Tendons

  3. Ligaments

  4. Nerves


Correct Option: C
Explanation:

A sprain is a stretching or tearing of ligaments which are the tough bands of fibrous tissue that connect two bones together in the joints. A sprain results in an overstretch or tear of the ligaments supporting that joint. 

So, the correct answer is 'ligaments'.

Dislocation of bones occurs in persons who have met with and met in accidents due to the

  1. Tendon break

  2. Break of skeletal muscle

  3. Ligament break

  4. Areolar tissue break


Correct Option: C
Explanation:

The ligament is the connective tissue which attaches two or more bones together to form a joint. When the ligament breaks, the two bones cannot be held together and dislocate. Generally, when the person met with an accident and the ligament is broken, there are chances that the person will suffer from the dislocation of the bones. 

Thus, the correct answer is option C. 

Bones become fragile due to

  1. Arthritis

  2. Osteoporosis

  3. Gout

  4. None of the above


Correct Option: B
Explanation:
  • Osteoporosis is defined as low bone mass and microarchitectural deterioration of the bone tissue, leading to enhanced bone fragility and a consequent increase in fracture risk.
  • It may occur due to various reasons such as calcium deficiency, increase in osteoclastic or osteoblastic activity, age, estrogen deficiency in females etc.
  • Hence bones become fragile (easily broken or damaged) due to osteoporosis.
  • So,the correct answer is 'Osteoporosis'.

To treat myasthenia gravis, 

  1. Acetylcholine esterase activity is inhibited

  2. Receptors on motor end plate are reduced

  3. Secretion from nerve terminals is reduced

  4. Secretion from nerve terminals is enhanced


Correct Option: A
Explanation:

Myasthenia gravis is a disease caused due to the antibodies produced by an immune system that blocks or destroy the receptor sites for a neurotransmitter called acetylcholine. The enzyme esterase or acetylcholine esterase break the acetylcholine and deactivates the neurotransmitter to stop muscle activation. 

During treatment of myasthenia gravis, it is prevented by using a chemical drug acetylcholinesterase inhibitor. These acetylcholinesterase inhibitors increase the amount of acetylcholine available and so help muscle activation and contraction.
So the correct option is 'Esterase activity is inhibited'.