Tag: antacids and antihistamines

Questions Related to antacids and antihistamines

The drug cimetidine was designed to:

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. prevent the interaction of histamine with receptors

  2. stimulates the secretion of pepsin

  3. reduce gaestro intestinal juices

  4. all of the above

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Correct Option: A,C
Explanation:

The drug cimetidine (Tegamet), was designed to prevent the interaction of histamine with the receptors present in the stomach wall. This resulted in release of lesser amount of acid. The importance of the drug was so much that it remained the largest selling drug in the world until another drug, ranitidine (Zantac), was discovered.

An antacid tablet weighing 1 g containing aluminium hydroxide as the only basic substance and the rest of its components being neutral, was dissolved in 200 mL of 0.1 M HCI. The excess HCI was back titrated and required  90 mL of 0.1 N base for exact neutralization. Mill equivalents of aluminum hydroxide in the sample of antacid tablet is 

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. 9

  2. 11

  3. 12

  4. 20

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Correct Option: B

The main function of an antiacid is

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. to neutralise body acid

  2. to neutralise body base

  3. both $a$ and $b$

  4. $None\ of\ these$

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Correct Option: A

Histamine is responsible for the nasal congestion associated with common cold and allergic response to pollen.

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. True

  2. False

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Correct Option: A
Explanation:

The pollen triggers these cells in nasal chambers, causing them to release histamine and the other chemicals. Histamine dilates the small blood vessels of the nose and fluids leak out into surrounding tissues causing allergy symptoms.

So, the above statement is true.

Examples of antacids are:

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. sodium hydroxide

  2. sodium bicarbonate

  3. magnesium hydroxide

  4. urea

Show answer
Correct Option: B,C
Explanation:

Antacids: Tension and mental stress escalate the level of acid in bile juice. This hyperacidity can be combated using bases like calcium carbonate, magnesium hydroxide or aluminium hydroxide in the form of tablets or aqueous suspensions. These react with hydrochloric acid in the stomach and neutralize it partially. Gelusil and Digene are two examples of antacids. Antacids must be basic but not enough to make it caustic. Hence, options B and C are appropriate.

Urea is responsible for the nasal congestion associated with common cold and allergic response to pollen.

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. True

  2. False

Show answer
Correct Option: B
Explanation:

The pollen triggers these cells in nasal chambers, causing them to release histamine and the other chemicals. Histamine dilates the small blood vessels of the nose and fluids leak out into surrounding tissues causing allergy symptoms.

So, the above statement is false.

Which of the following is a use of $Mg(OH) _2$?

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. It is used in fire extinguisher as a foaming agent.

  2. It is used in the preparation of fertilizers.

  3. It is used in removing stains of grease from clothes.

  4. It is used as an antacid.

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Correct Option: D
Explanation:

$Mg(OH) _2$ is used as an antacid to neutralize the acidity in the stomach.

________ work by counteracting (neutralising) the acid in your stomach. 

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. Disinfectants

  2. Antibiotics

  3. Antacids

  4. Anti-depressants

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Correct Option: C
Explanation:

Antacids neutralize the acid made by your stomach, curing various problems like heartburn, upset stomach, etc. Generally, they do not have any side effects.

Which of the following is an antacid?

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. Rantidine

  2. Histamine

  3. Cimetidine

  4. All of the above

Show answer
Correct Option: D
Explanation:

An antacid is a substance which neutralizes stomach acidity, which in turn relieves heartburn, indigestion or stomach upset.
All of these are the examples of antacids.

Which of the following is an antihistamine?

chemistry medicinal chemistry antacids and antihistamines therapeutic action of different classes of drugs ph regulation of the stomach

  1. Brompheniramine

  2. Equanil

  3. Ranitidine

  4. Cimetidine

Show answer
Correct Option: A
Explanation:

Antihistamine is a drug that inhibits the physiological effects of histamine, used especially in the treatment of allergies.


Brompheniramine is an antihistamine.

Equanil is a tranquilizer.

Ranitidine and Cimetidine are antacids.

Hence the correct option is A.