Tag: blood clotting and healing of wounds

Questions Related to blood clotting and healing of wounds

Blood agglutination tests are used in

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Antigen antibody reaction

  2. Animal relations

  3. Immunity

  4. None of the above

Show answer
Correct Option: A
Explanation:
Blood agglutination tests are used in Antigen-antibody reactions. The clumping of particles is called as agglutination. Clumping occurs when an antigen is mixed with its corresponding antibody. When people are given blood transfusions of the wrong blood group, the antibodies react with the incorrectly transfused blood group and as a result, the erythrocytes clump up and stick together causing them to agglutinate 
So, the correct answer is 'Antigen-antibody reaction'.

Blood precipitation test was proposed by

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Wallace

  2. Nuttal

  3. Bateson

  4. Needham

Show answer
Correct Option: A
Explanation:
Blood precipitation test was proposed by Wallace. Blood precipitation reactions are based on the interaction between antibodies and antigens. They are based on two soluble reactants (Antigen and antibody) that come together to make one insoluble product(Antigen-Antibody complex), the precipitate. 
So, the correct answer is 'Wallace'.

Conversion of fibrinogen to fibrin is catalysed by

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Thrombin

  2. Prothrombin

  3. Thromboplastin

  4. All of these

Show answer
Correct Option: A
Explanation:
Thrombin catalyzes the conversion of fibrinogen (factor I)—a soluble plasma protein into long, sticky threads of insoluble fibrin . The fibrin threads form a mesh that traps platelets, blood cells, and plasma.The fibrin mesh work begins to contract in a short period of time and prevents blood loss. 
So, the correct answer is 'Thrombin'

During the process of blood coagulation, vitamin k helps in

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. The formation of thromboplastin

  2. The conversion of fibrinogen to fibrin

  3. The conversion of prothrombin to thrombin

  4. The formation of prothrombin

Show answer
Correct Option: D
Explanation:

Vitamin K helps in the synthesis of prothrombin in the liver.

So, the correct answer is 'The formation of prothrombin'

In the clotting mechanism pathway, thrombin activates the factors

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. XI, VIII, V

  2. XI, IX, X

  3. VIII, X, V

  4. only XIII

Show answer
Correct Option: D
Explanation:

In the blood coagulation pathway thrombin activates Factor XIII to XIIIa that helps in binding of fibrin monomers to form the stable fibrin filament.

So, the correct answer is 'only XIII'

Which proteolytic enzyme induces lysis of fibrin during fibrinolysis?

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Fibrin

  2. Thrombin

  3. Plasmin

  4. Platelet factor VIII

Show answer
Correct Option: C
Explanation:

Plasmin is the proteolytic enzyme that induces lysis of fibrin to fibrin degradation products during fibrinolysis (enzymatic breakdown of fibrin during blood clots)

So, the correct answer is 'Plasmin'

Mark the pair of substances among the following which is essential for coagulation of blood.

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Heparin and calcium ions

  2. Calcium ions and platelet factors

  3. Oxalates and citrates

  4. Platelet factors and heparin

Show answer
Correct Option: B
Explanation:

Calcium ions and platelets are essential factors for clotting of blood. During some injury, the platelets release inactivated platelet factors that are involved in the activation of other factors involved in the formation of clots in the blood. Calcium ions in the blood catalyze the activation of many factors involved in clot formation like factor VIII, factor IX, factor V and factor XIII.

Thus, the correct answer is 'Calcium ions and platelet factors.'

Which of these are necessary for initiation of blood clotting process?

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Prothrombinase and thrombin

  2. Tissue factor hageman factor and $Ca^{2+}$

  3. Prothrobinase and $K^{2+}$

  4. Prothrobinase , tissue factor and $Ca^{2+}$

Show answer
Correct Option: B
Explanation:

There are two processes that can initiate clotting

  1. A very rapid process the so-called extrinsic pathway 
  2. A slower but larger intrinsic pathway
In the extrinsic pathway- Damaged cells display a surface protein called tissue factor
In the intrinsic pathway- Factor 12 (XII) (also called the Hageman factor) circulates in the blood.
Calcium ions are required for the promotion or acceleration of blood clotting pathways
So correct option is B, Tissue factor hageman factor and $Ca^{2+}$.

Removal of calcium from freshly collected blood will

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Prevent clotting

  2. Result in clotting

  3. Prevent oxidation of haemoglobin

  4. Cause haemolysis

Show answer
Correct Option: A
Explanation:

Clotting requires calcium ions ($Ca2^+$), which is why blood banks use a chelating agent to bind the calcium in donated blood, so the blood will not clot in the bag.

Mineral essential for the coagulation of blood is

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Potassium

  2. Magnesium

  3. Calcium

  4. Sodium

Show answer
Correct Option: C
Explanation:

All the reactions which happen during the clotting process require calcium ions for their occurrence. Calcium works together with vitamin K and a protein called as fibrinogen in the clotting cascade. Without adequate levels of calcium and vitamin K, blood will take longer to clot and if both nutrients are missing it could be fatal. Therefore, the correct answer is option C.