Tag: coagulation of blood

Questions Related to coagulation of blood

The vitamin essential for the synthesis of prothrombin is 

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Vitamin K

  2. Vitamin E

  3. Vitamin A

  4. Vitamin D

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Correct Option: A
Explanation:

Prothrombin is a precursor of the clotting factor thrombin. Prothrombin forms thrombin in the cascade clotting reaction. It is produced in the liver cells in the presence of vitamin K.

The blood does not clot inside the body because of

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  1. Oxygenation of blood

  2. Movement of blood

  3. Heparin in blood

  4. Absence of fibrinogen in blood

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Correct Option: C
Explanation:
A blood clot is actually the thickened mass formed by the blood platelets and stops the blood profusely out of any cuts or wounds. However, in general and in healthy condition blood does not form clots inside the body due to the presence of heparin an anticoagulant that is secreted by the basophils and mast  cells of the blood. Since, this is released into the blood vessels it prevents the formation of clots in them
So, the correct answer is 'Heparin in blood'

Which option is correct for the formation of intrinsic factor-X activator complex for blood coagulation?

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  1. Activated Christmas factor + AHG + phospholipid + $Ca^{+2}$

  2. Inactivated Christmas factor + AHG + phospholipid +$Ca^{+2}$

  3. Convertin + AHG + $Ca^{+2}$+ FSF

  4. Phospholipid - protein complex + Proconvertin

Show answer
Correct Option: A
Explanation:

The Hageman factor XII is activated when it comes in contact with a damaged blood vessel. The activated Hageman factor activates the factor XI. The activated factor XI acts on Chrishmas factor IX to form activated IXa. Factor IXa combines with AHG VIII phospholipid and calcium ions to form a complex called intrinsic factor X activator complex. Thus the correct answer is option A.

Match the following Columns I, II with III.

Column I(Common name) Column II(Roman numerical designation) Column III(Activation product)
A. Prothrombin 1. I (i) Convertin
B. Proconvertin 2. V (ii) Fibrin
C. Fibrinogen 3. II (iii) Thrombin
D. Proaccelerin 4. VII (iv) Accelerin
biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. A- 3- (iii), B- 4- (i), C- 1- (ii), D- 2- (iv)

  2. D- 4- (ii), B- 3- (iii) C- 2- (iv), A- 1- (i)

  3. C- 3- (iii), A- 4- (ii), B- 1- (iv), D- 2- (i)

  4. A- 3- (iii),C-  4- (i), D- 2- (ii), B- 1- (iv)

Show answer
Correct Option: A
Explanation:

The following enzymes are involved in the mechanism of blood clotting in human.

Column I(Common name) Column II(Roman numerical designation) Column III(Activation product)
A. Prothrombin $3.$ II (iii) Thrombin
B. Proconvertin $4.$ VII (ii) Convertin
C. Fibrinogen $1.$ I (ii) Fibrin
D. Proaccelerin $2.$ V (iv) Accelerin

Fill in the blanks with suitable words given below:
The liquid part of coagulated blood is known as _________

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  1. Serum

  2. Fibrinogen

  3. Hemoglobin

  4. Pulmonary

  5. Sphygmomanometer

  6. Ventricles

Show answer
Correct Option: A
Explanation:

The liquid part of coagulated blood is known as serum. It is the liquid portion of blood clot . It includes all proteins not used in clotting of blood and all the electrolytes, hormones, antibodies, antigens etc..

Hence, the correct answer is 'Serum' .

Choose the correct answer from the alternatives given.
Which of the following ions is involved in blood clotting?

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  1. $K^+$

  2. $Na^+$

  3. $Fe^{+++}$

  4. $Ca^{++}$

Show answer
Correct Option: D
Explanation:

Blood coagulation is a complex biochemical process involving platelets and many proteins (enzymes).  Calcium is involved at several steps in the blood clotting, including the activation of the platelets, activation of clotting factors and enzymes which are present in the blood in inactive form. The $Ca^{++}$ ions bind with prothrombin and covert it into active form thrombin. The thrombin in turn converts fibrinogen into fibrin (a thread like protein) which traps red blood cells and helps in the formation of clot.

So, the correct option is '$Ca^{++}$'.

Sodium oxalate prevents blood clotting due to

biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

  1. Blocking of fibrinogen transformation

  2. Covering RBC

  3. Inhibiting activity of clotting factor of plasma

  4. Combining with calcium ions of blood

Show answer
Correct Option: D
Explanation:

Sodium oxalate, like citrates, can be used to remove calcium ions (Ca${^2}$${^+}$) from blood plasma. It thus prevents blood from clotting. In the presence of calcium ions and other clotting factors, factor X activates an enzyme called prothrombin activator. This enzyme then converts the plasma protein prothrombin into thrombin. Thrombin is an enzyme that, in turn, converts fibrinogen to fibrin.