Tag: drugs and their classification

Questions Related to drugs and their classification

The greatest number of antimicrobic allergies is reported for which drug?

  1. Sulfonamides

  2. Quinolones

  3. Tetracycline

  4. Penicillin


Correct Option: D
Explanation:

Penicillin, one of the first and still one of the most widely used antibiotic agents, derived from the Penicillium mold.In 1928 Scottish bacteriologist Alexander Fleming first observed that colonies of the bacterium staphylococcus aureus failed to grow in those area of a culture that had been accidentally contaminated by the green mold Penicillium notatum.The greatest number of antimicrobic allergies is also reported for Penicillins 

Which antibacterial drug does not inhibit protein synthesis?

  1. Tetracycline

  2. Penicillin

  3. Chloramphenicol

  4. Erythromycin


Correct Option: C
Explanation:

Chloramphenicol interact acts with SOS subunit, of ribosome and prevents the formation of peptide bonds when chloramphenicol is around, amino acid beads can't be linked together into polypeptide strings.

Drugs, that affect the bacterial cell wall, are active only against what type of cells?

  1. Gram negative

  2. Young, actively growing

  3. Dormant

  4. Gram variable


Correct Option: B
Explanation:

Drugs affect the bacterial cell wall which is made of phospholipids. These drugs are active against young and actively growing bacteria.


Hence, the correct option is $B$

Which of the following statements is accurate in explaining why Gram negative bacteria are generally more resistant to penicillins than Gram positive bacteria?

  1. Gram negative bacteria have a thicker cell wall

  2. Gram negative bacteria have an outer hydrophilic membrane that acts as an extra barrier

  3. Gram negative bacteria can concentrate $\beta$-lactamase enzymes in the periplasmic space

  4. Gram negative bacteria produce smaller quantities of transpeptidase enzyme


Correct Option: C
Explanation:

Gram negative bacteria can concentrate $\beta$-lactamase enzymes in the perplasmic space between the cell wall and the outer membrane. Some Gram positive bacteria can produce $\beta$-lactamase enzyme, but these enzymes diffuse away from the cell because there is no outer membrane to trap them . Thus, they are less effective than $\beta$-lactamases produced by Gram negative bacteria.

The golden age of antibiotics began in 1928 with Sir Alexander Fleming's discovery of an antibacterial compound he called:

  1. salvarsan

  2. arsenic

  3. sulfonamide

  4. penicillin


Correct Option: D
Explanation:

Penicillin was discovered in 1928 by Scottish scientist Alexander Fleming. People began using it to treat infections in 1942. There are several enhanced penicillin families which are effective against additional bacteria; these include the antistaphylococcal penicillins, aminopenicillins, and the antipseudomonal penicillins. They are derived from Penicillium fungi.

Birth control pills as antifertility drugs, essentially contain a mixture of synthetic estrogen and _____________  hormones.

  1. protonsil

  2. progesterone derivative

  3. chloroxylenol

  4. quaternary ammonium salt


Correct Option: B
Explanation:

Estrogen and progesterone are the female hormones that are associated with ovulation and menstruation in females. Besides this, both play important role in pregnancy.

The birth control pills are the derivative of these estrogens and progesterone.

The birth control pills are which kind of drug?

  1. analgesics

  2. tranquilizers

  3. sulphapyridine

  4. antifertility


Correct Option: D
Explanation:

Antifertility agents are drugs that control fertility and are also called oral contraceptives. These drugs affect and are involved in the menstrual cycle and ovulation in females. Estrogen and progesterone in combined form are given as birth control pills. The antifertility substance is deemed to be active in females when it prevents fertilization, prevent ovulation, implantation, and destroys the zygote or causes abortion.

The estrogen derivative which is used in combination with progesterone derivative is __________.

  1. Novestrol

  2. Dysidazirine

  3. Chloramphenicol

  4. Amoxycillin


Correct Option: A
Explanation:

Ethinylestradiol (Novestrol) is an estrogen medication which is used widely in birth control pills in combination with progestins. It is also occasionally used as a component of menopausal hormone therapy for the treatment of menopausal symptoms in combination with progestins.

Most widely used antifertility drug is:

  1. vancomycin

  2. ranitidine

  3. norethindrone

  4. none of these


Correct Option: C
Explanation:

Norethindrone is a synthetic progesterone most commonly used antifertility drugs. A chemical substance which is used to check pregnancy in women is called antifertility drug.

Which of the following are the antispasmodics?

  1. Dicycloverine

  2. Atropine

  3. Propantheline

  4. All the above


Correct Option: D
Explanation:

There are two main types, as follows.

Antimuscarinics such as:

Dicycloverine

Hyoscine

Atropine

Propanthaline

Smooth muscle relaxants such as:

  • Alverine
  • Mebeverine
  • Peppermint oil
  • Hence option D is correct.