Tag: molecular basis of inheritance

Questions Related to molecular basis of inheritance

The most detailed genetic map is 

  1. Cytogenetic

  2. Linkage

  3. Physical

  4. Sequence


Correct Option: D

Which of the following is the largest gene in humans?

  1. Dystrophin

  2. Insulin

  3. Titin

  4. Phosphofructokinase


Correct Option: A
Explanation:
Dystrophin is a cytoplasmic rod-shaped protein consisting of which is chiefly situated in skeletal & cardiac muscles. It's formation includes the largest gene with 2.6 Mb and 97 exons. Small quantity of dystrophin is also present in the brain nerve cells.
So, the correct answer is 'Dystrophin'

Which of the following can improve the diagnosis of many genetic disorder?

  1. PCR

  2. Human genome project

  3. DNA fingerprinting

  4. None of the above


Correct Option: B

Which of the following is not an aim of human genome project?

  1. To sequence the genome of selected model organism

  2. Eliminate all disease

  3. To sequence EST fragments of cDNA in both human and mice

  4. To develop computational tool for analysing sequence information


Correct Option: B
Explanation:

Human Genome Project was a 13-year-old project started by US department of energy and National Institute of Health for sequencing the Human Genome.

The main objectives of the HGP were to- 

  • Determine the sequence of 3.2 billion base pairs of Human Genome.
  • Identify all the genes of the genome and determine their functions.
  • To store this information and database.
  • This project may result in many ethical legal and social issue which needs to be addressed and solved.

 So, the correct option is 'Eliminate all disease'

Lily has .......... more DNA than human genome.

  1. 10 times

  2. 4 times

  3. 20 times

  4. 18 times


Correct Option: D
Explanation:

The main aim of the Human Genome Project was to determine the sequence of 3.2 billion base pairs of Human Genome and to identify their functions.

It was found that Human Genome contains around 30,000 jeans and 99.9% of nucleotide bases and all human beings are same.
The amount of genes present in Lily is 18 times more than the Human Genome.

So, the correct option is '18times'.

Which of the following provides fund for the human genome project?

  1. NIH

  2. DOE

  3. Both A and B

  4. NIH, DOE and ELSI


Correct Option: C
Explanation:

The Human Genome Project was started by US department of energy and National Institute of Health and this was done for the sequencing of human genome.

It was approximately quoted to be around 9 billion US dollars.
So, the correct option is 'Both A and B'

Human genome project was

discovered by

  1. Francis Collins and Roderick

  2. Watson and Crick

  3. Beadle and Tatum

  4. Paul Berg and Wollman


Correct Option: A

Human genome project was launched in

  1. 1980

  2. 1987

  3. 1990

  4. 1993


Correct Option: C
Explanation:

Human Genome Project was launched in 1990 by coordination of US Department of Energy and National Institute of Health. The 13-year mega project was aimed to sequence complete 3 billion DNA base pairs that make up human genome. So, the correct answer is ' 1990'.

Human genome contains base pairs

  1. 2.5 million

  2. 25 million

  3. 27.2 million

  4. 3.2 billion


Correct Option: D
Explanation:

There are four bases adenine (A), thymine (T), guanine (G) and cytosine (C) present in humans. Bases on opposite strands pair specifically as an A always pairs with a T, and a C always with a G. The human genome contains approximately 3.2 billion of these base pairs, which reside in the 23 pairs of chromosomes within the nucleus of all our cells.

So, the correct option is '3.2 billion'.

Human genome project was launched by 

  1. Khorana and others

  2. Bhabha Institute

  3. U.S Department of Energy and National Institute of Health

  4. NASA


Correct Option: C