Tag: antibodies and antitoxin

Questions Related to antibodies and antitoxin

................  is associated with allergic reactions

  1. IgE

  2. IgG

  3. IgA

  4. IgM


Correct Option: A
Explanation:

Antibodies are the immunoglobulins which are produced in response to the antigen. The immunoglobulin E antibodies or IgE binds to an allergen and trigger the release of inflammatory chemicals such as histamine.
Therefore, the correct answer is option A.

Antibody is formed by _____________.

  1. Protein

  2. Carbohydrate

  3. Nucleic acid

  4. Lipid


Correct Option: A

Select the correct statement with respect to diseases and immunisation.

  1. If due to some reason B and T-Lymphocytes are damaged, the body will not produce antibodies against a pathogen.

  2. Injection of dead or inactivated pathogens causes passive immunity.

  3. Certain protozoans have been used to mass produce hepatitis B vaccine.

  4. Injection of snake antivenom against snake bite is an example of active immunisation.


Correct Option: A
Explanation:

Clone of B-cells is called as plasma cells which produce antibodies. Helper T-cells secrete IL-2 (interleukin-2) which stimulate B cells to produce antibodies. For example iInjection of snake antivenom against snake bite that provides artificially acquired passive immunity. Thus, the correct answer is option A.

A substance produced by the host in response to an infection or foreign structure is 

  1. Antigen

  2. Toxin

  3. Hormone

  4. Antibody


Correct Option: D
Explanation:

An antibody is a type of proteinaceous substance produced by the body's immune system when it detects harmful substances called antigens. Examples of antigens include microorganisms (bacteria, fungi, parasites and viruses) and chemicals. Each type of antibody is unique and defends the body against one specific type of antigen.

Antibodies are secreted by

  1. T-lymphocytes

  2. B-lymphocytes

  3. Both A and B

  4. Natural killer cell


Correct Option: B
Explanation:

An antibody or immunoglobulin is a  proteinaceous compound produced mainly by differentiated plasma cells i.e., B lymphocytes. It is used by the immune system to identify and neutralize pathogens such as bacteria and viruses. Thus, the correct answer is option B.

Shape of antibody is

  1. Y shaped

  2. S shaped

  3. T shaped

  4. R shaped


Correct Option: A
Explanation:
  • Antibodies are the Y-shaped proteinaceous compound. Each is made up of 2 heavy chains and 2 light chains. 
  • An antibody is made up of a variable region and a constant region, and the region that changes to various structures depending on differences in antigens is called the variable region, and the region that has a constant structure is called the constant region.

    Hence, option A is correct.

A person who has been infected with a virus in the past can be determined by the presence of

  1. Antigens

  2. Antibodies

  3. Macrophages

  4. Pathogens

  5. Natural killer cells


Correct Option: B
Explanation:

The encounter of B cell with a specific antigen activates its clonal expansion which in turn gives rise to plasma cell and memory cells.  Memory cells are the B cells (antibodies) responsible for long-term immunity and confirm the previous encounter of a person with the specific virus. Antigens are foreign substances that induce the immune system to produce antibodies. Disease-causing organisms are called as pathogens. Natural killer cells and macrophages are components of immune system. So, the correct answer is option D.

Antibodies in are complex

  1. Prostaglandins

  2. Glycoproteins

  3. Lipoproteins

  4. Steroids


Correct Option: B
Explanation:

An antibody is a protein which is produced in response to the antigen by the plasma cells. Antibodies are $\gamma$-globulin proteins that have sugar groups attached to amino acid chains. They can be classified as glycoproteins. These are y-shaped. So, the correct answer is option B.

The cells that actually release the antibodies are

  1. Helper T-cells

  2. Cytotoxic T-cells

  3. Plasma cells

  4. Memory cells


Correct Option: C
Explanation:

Plasma cells, also known as plasma B cells or plasmocytes are white blood cells that secrete large volumes of antibodies. They are transported by the blood plasma and the lymphatic system. Plasma cells are originated in the bone marrow, B cells differentiate into plasma cells that produce antibody molecules. Once released into the blood and lymph, these antibody molecules bind to the target antigen (foreign substance) and initiate its neutralization or destruction.

So, the correct answer is 'Plasma cells'.

Lysis of foreign cells is mediated through 

  1. IgM and IgG

  2. IgG and IgA

  3. IgA and IgD

  4. IgD and IgE


Correct Option: A
Explanation:

  • Immunoglobulin M (IgM) is one of several forms of the antibody that are produced by vertebrates. 
  • IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. 
  • IgM can bind to complement component and activate the classical pathway, leading to opsonization of antigens and cytolysis (lysis of foreign cells).
  • IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. 
  • Coating of IgG on pathogen surfaces (known as opsonization) allows their recognition and ingestion by phagocytic immune cells leading to the lysis of foreign cells.
So, the correct answer is 'IgM and IgG'.