Tag: antibodies and antitoxin

Questions Related to antibodies and antitoxin

B-cells produce antibodies in response to instruction received from 

  1. Killer T-cells

  2. Suppressor T-cells

  3. Mast cells

  4. Helper T-cells


Correct Option: D
Explanation:

B cells, also known as B lymphocytes are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system by secreting antibodies. B-cells bind to an antigen, receive help from a cognate helper T cell and differentiate into a plasma cell that secretes large amounts of antibodies.

So, the correct answer is 'Helper T-cells'.

Number of antibodies produced per day during an infection can be 

  1. 2 trillion

  2. 20 trillion

  3. 200 trillion

  4. 2000 trillion


Correct Option: B

Antibodies that function in innate immunity are

  1. IgM

  2. IgE

  3. IgA

  4. IgD


Correct Option: C
Explanation:
Immunoglobulin A (IgA) is an antibody that plays a crucial role in the immune function of mucous membranes. IgA plays an important role in innate immunity which acts as an important first line of defence. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes, thus sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions.
So, the correct answer is 'IgA'.

Antibody formation and immunity production by globulin protein is found in 

  1. Haemoglobin of RBC's

  2. Blood platelets

  3. Plasma

  4. Cytoplasm of RBC's


Correct Option: C
Explanation:

An antibody is produced by plasma cell. This plasma cell /plasma B cells/effector B cell are white blood cells that secrete large volumes of antibodies. Plasma cell originates in the bone marrow. B cell differentiate into a plasma cell that produces antibody molecules. These are transported by the blood plasma and the lymphatic system. Once these are released into the blood and lymph, these antibody molecules bind to the target antigen and initiate its neutralization or destruction.

So the correct answer is 'Plasma'.

Immunoglobulin that increases in number during allergy is 

  1. IgA

  2. IgE

  3. IgG

  4. IgM


Correct Option: B
Explanation:

Immunoglobulin E (IgE) is a type of antibody that has been found only in mammals. IgE is synthesised by plasma cells. IgE has an essential role in type I hypersensitivity (allergy) which includes allergic diseases, such as allergic asthma, sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis.

So, the correct answer is 'IgE'.

Antibody

  1. Induces formation of antigen

  2. Helps in the production of WBC

  3. Is formed by WBC

  4. None of the above


Correct Option: C
Explanation:

An antibody, also known as an immunoglobulin is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. Antibodies are secreted by B lymphocytes of the adaptive immune system, mostly by differentiated B cells called plasma cells. Lymphocyte is a type of WBC. Hence, Antibody is formed by WBC.

So, the correct answer is 'Is formed by WBC'.

Gamma-globulins are synthesised in

  1. Lymph and lymph nodes

  2. Liver

  3. Bone marrow

  4. Kidney


Correct Option: A
Explanation:

Globulins are immune molecules that are produced by the immune system in response to the invasion of the body of agents that are perceived by the system as being foreign. Gamma globulins belong to the class of globulins. Most significant globulins are immunoglobulins. Gamma globulins are synthesized in cells of the immune system known as lymphocytes, lymph nodes, lymph and plasma cells. 

So, the correct answer is 'Lymph and lymph nodes'.

Immunoglobin found in serum (of new born) is 

  1. IgG

  2. IgA

  3. IgM

  4. IgN


Correct Option: A
Explanation:

Immunoglobulin G (IgG) is a type of antibody., representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. The primary immunoglobulin of the newborn is the maternal IgG as this is the only immunoglobulin to cross the placental barrier. Hence, IgG is the immunoglobulin which is found in the serum of newborn babies.

So, the correct answer is 'IgG'.

Binding of antigen to antibody is through

  1. Electrostatic intereactions

  2. Covalent bonds

  3. Disulphide bridges

  4. Amide formation


Correct Option: A
Explanation:

Antibodies bind antigens through weak chemical interactions, and bonding is essentially non-covalent. Electrostatic interactions, hydrogen bonds, van der Waals forces, and hydrophobic interactions are all known to be involved depending on the interaction sites.

So, the correct answer is 'Electrostatic intereactions'.

Resistance against disease is provided by 

  1. Antigens

  2. Immunoglobulins

  3. Histamine

  4. HLA proteins


Correct Option: B
Explanation:

An antibody, also known as an immunoglobulin (Ig) is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. Antibodies or immunoglobulins provides resistance against disease by neutralising antigens which are responsible for the disease. Antibodies are secreted by B-lymphocytes, mostly by differentiated B cells called plasma cells.

So, the correct answer is 'Immunoglobulins'.