Tag: immune system

Questions Related to immune system

Prolonged use of  which of the following immunosuppresants may cause immunosuppression of both innate and adaptive immunity?

  1. Tetracycline

  2. Opioids

  3. Analgesics

  4. All of the above


Correct Option: B

 ............ is a immunosuppressant which is mainly used as a folic acid analogue.

  1. Methotrexate

  2. Tetracycline

  3. Azathioprine

  4. None of these


Correct Option: A
Explanation:

Methotrexate is an immunosuppressant mainly used as a folic acid analogue. It is known as amethopterin is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy and medical abortions. Used for include breast cancer, leukemia, lung cancer, lymphoma.

Which of the following class of immunosuppresants inhibit both T and B cell proliferation?

  1. Glucocorticoids

  2. Cytostatics

  3. Androgen

  4. Antibody


Correct Option: B
Explanation:

Cytostatics inhibit cell division. They affect the proliferation of both T cells and B cells. Due to their highest effectiveness.


 Which of the following immunosuppressant drugs is used is to slow down the progression of multiple sclerosis?

  1. IFN

  2. Mycophenolate

  3. Beta blocker

  4. Both A and B


Correct Option: A
Explanation:

IFN is the immunosuppressive drug to slow down the progression of multiple sclerosis. It is used to treat various cancers and virus infections. It is same as protein that your body naturally produces. It is through to work by affecting cell function and body's natural defenses in many ways.

 ............. is a self-tissue transferred from one body site to another in the same individual.

  1. Autograft

  2. Isograft

  3. Xenograft

  4. None of the above


Correct Option: A

The transfer of tissue in monozygous twins can be categorized as

  1. Isograft.

  2. Autograft.

  3. Allograft.

  4. None of the above.


Correct Option: A
Explanation:

A- An isograft is a graft of tissue between two individuals who are genetically identical i.e. monozygotic twins.Transplant rejection in such cases never occurs.

An organ donation from one person to another can be categorized as 

  1. Allograft.

  2. Xenograft.

  3. Autograft.

  4. All of the above.


Correct Option: A
Explanation:

A- Allograft or allotransplant is the transplant of cells, tissues, or organs to a recipient from a genetically non-identical donor of same species. Most of the organ or tissue transplants in human are allografts.  

Graft recognizes the recipient as foreign which can be seen in

  1. Transplantation rejection.

  2. Graft versus host disease.

  3. Passive immunization.

  4. Both A and B.


Correct Option: B
Explanation:
Graft versus host disease is a condition that might occur after an allogeneic transplant. In this, the donated bone marrow or peripheral blood stem cells view the recipient's body as foreign, and thus attack the body. 
So, the correct answer is option B.

Graft versus host disease mostly occurs after 

  1. Xenograft transplant.

  2. Allogenic transplant.

  3. Isograft transplant.

  4. None of the above.


Correct Option: B

The graft rejection takes place due to the presence of ________

  1. T cells

  2. B cells

  3. Mast cells

  4. None of the above


Correct Option: A