Tag: immune system

Questions Related to immune system

Antivenom injection contains preformed antibodies while polio drops that are administered into the body contain

  1. Attenuated pathogens

  2. Activated pathogens

  3. Harvested antibodies

  4. Gamma globulin


Correct Option: A
Explanation:

  • Antivenom injection is an antiserum (preformed antibodies) which is obtained from the snake poison and it is transferred to the person with a snake bite. It is used to provide immediate immunity in case of emergency.
  • Polio vaccines are vaccines used to prevent poliomyelitis (polio). Two types are used - an inactivated poliovirus (antigen) given by injection and an attenuated poliovirus (antigen) given by mouth. The inactivated polio vaccines are very safe. Mild redness or pain may occur at the site of injection. Oral polio vaccines cause vaccine-associated paralytic poliomyelitis.
So, the correct answer is 'Attenuated pathogens'.

Suspension of attenuated pathogen that stimulates antibody formation is

  1. Antitoxin

  2. Antibiotic

  3. Vaccine

  4. Sera


Correct Option: C
Explanation:

A vaccine is a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically contains a suspension of disease-causing microorganism and is often made from weakened (attenuated) or killed forms of the microbe, its toxins, or one of its surface proteins.  The agent stimulates the body's immune system and produces antibodies.

So, the correct answer is 'Vaccine'.

Which one of the following cannot be used for preparation of vaccination against plague?

  1. Heat killed suspension of virulent bacteria

  2. Formaline inactivated suspension of virulent bacteria

  3. A virulent live bacteria

  4. Synthetic capsular polysaccharide material


Correct Option: D
Explanation:

  • Plague is an infectious disease caused by the bacterium Yersinia pestis.
  •  Killed bacteria have been used since 1890 but are less effective against pneumonic plague so that recently live vaccines of an attenuated type and recombination protein vaccines have been developed to prevent the disease.
  • Synthetic capsular polysaccharide vaccines are used for the treatment of pneumonia and meningitis. 
  • Hence, Synthetic capsular polysaccharide material cannot be used for the preparation of vaccination against the plague. 
  • So, the correct answer is 'Synthetic capsular polysaccharide material'.

What is introduced in the body during small pox vaccination?

  1. Antibodies

  2. leucocytes

  3. Antibiotics

  4. Attenuated virus


Correct Option: D
Explanation:

Smallpox is a serious viral disorder caused by the variola virus. Variola virus is an orthopoxvirus, an enveloped DNA virus. The infection starts by exposure of the virus in the nasopharynx and characterized by fever and malaise. 

A vaccine is prepared from the killed and weakened form of a pathogen that is similar to the disease-causing agent. This vaccine is injected into an individual to induce the immune system against the microbes. The vaccine for smallpox is prepared from a weakened form of variola virus. Thus, during smallpox vaccination attenuated virus is introduced in the body that induces immunity against the infection.

Match the list and find the correct answer.

   LIST I   LIST II 
 a  Conjugate vaccine  Human papilloma virus
 b  Toxoid vaccine ii   Haemophilus influenzae
 c  Attenuated whole agent vaccine  iii   Bubonic plague
 d  Inactivated whole agent vaccine iv   Yellow fever
     v  Diphtheria
  1. a - i, b - iv, c - v, d - ii

  2. a - ii, b - v, c - iv, d - iii

  3. a - i, b - ii, c - iii, d - v

  4. a - ii, b - iii, c - i, d - iv


Correct Option: B
Explanation:
  • Conjugate vaccines combine a weak antigen with a strong antigen so that the immune system has a stronger response to the weak antigen. Example: Haemophilus influenza.
  •  Toxoid vaccine is made from a toxin (poison) that has been made harmless but that helps in an immune response against the toxin. They are based on the toxin produced by certain bacteria (e.g. tetanus or diphtheria). An
  • The attenuated vaccine is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable. Example are Measles, mumps, rubella, yellow fever. 
  • Inactivated whole-cell vaccines are made from microorganisms (viruses, bacteria, other) that have been killed through physical or chemical processes. An example is Polio, bubonic plague, Hepatitis A.

A person likely to develop tetanus is immunised by giving

  1. Weakened germs

  2. Pre-formed germs

  3. Dead grems

  4. Wide spectrum antibodies


Correct Option: B
Explanation:

Tetanus vaccine, also known as tetanus toxoid (TT), is an inactive vaccine used to prevent tetanus. A person likely to develop tetanus is immunised by giving pre-formed antibodies and it produces passive immunity. In passive immunity, the antibodies are produced in some other animals in response to given antigen. These pre-formed antibodies are then injected into the humans at the time of need or emergency.

So, the correct answer is 'Pre-formed germs'.

BCG vaccine provides protection against 

  1. Measles

  2. T.B

  3. Cholera

  4. Small pox


Correct Option: B
Explanation:
  • Tuberculosis is an infectious disease usually caused by Mycobacterium tuberculosis bacteria. Tuberculosis generally affects the lungs, but can also affect other parts of the body. The symptoms of active TB is a chronic cough with blood-containing sputum, fever, night sweats, and weight loss.

  • Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). In most tuberculosis (TB) endemic countries, bacillus Calmette Guérin (BCG) is usually given around birth to prevent severe TB in infants.

  • Hence BCG vaccine provides protection against TB.

  • So, the correct answer is 'T B'.

The Diptheria, Pertussis, Tetanus (DPT) vaccine consists of ____________________.

  1. live attenuated strains of Diphtheria, Pertussis, Tetanus

  2. toxoid of Diptheria, Tetanus and heat killed whole cells of Pertussis

  3. whole cells lysate of Diphtheria, Pertussis, Tetanus

  4. heat killed strains of Diptheria, Pertussis, Tetanus


Correct Option: B

The vaccination against small pox means the introduction of

  1. weakened germs

  2. lymphocytes

  3. leucocytes

  4. antibodies


Correct Option: A
Explanation:

The smallpox vaccine protects people from smallpox by helping their bodies develop immunity to smallpox. The vaccine is made from a virus called vaccinia, which is a poxvirus similar to smallpox, but less harmful. The smallpox vaccine contains live vaccinia virus, not a killed or weakened virus like many other vaccines. For that reason, people who are vaccinated must take precautions when caring for the place on their arm where they were vaccinated, so they can prevent the vaccinia virus from spreading. The vaccine does not contain the smallpox virus and cannot give you smallpox. For most people with healthy immune systems, live virus vaccines are effective and safe. Smallpox vaccination can protect you from smallpox for about 3 to 5 years. After that time, its ability to protect you decreases. If you need long-term protection, you may need to get a booster vaccination. 


So, the correct option is 'Weakened germs'.

Which one of the following can not be used for preparation of vaccines against plague?

  1. Avirulent live bacteria

  2. Synthetic capsular polysaccharide material

  3. Heat-killed suspension of virulent bacteria

  4. Formalin-inactivated suspensions of virulent bacteria


Correct Option: B
Explanation:
Synthetic capsular polysaccharide vaccines are available for treatment of pneumonia and meningitis. 
Vaccines against plague are prepared from the Formalin-inactivated suspensions of virulent bacteria, Avirulent live bacteria and Heat-killed suspension of virulent bacteria
So the correct option is 'Synthetic capsular polysaccharide material'.