Tag: blood clotting

Questions Related to blood clotting

Heparin in blood is released from  

  1. Clumped platelets

  2. Mast-cell granules

  3. Non-granulocytes

  4. Granulocytes


Correct Option: B
Explanation:
Mast-cell is a type of granulocyte. It contains basophil granules that secrete heparin and histamine in blood. They play important role in wound healing. 
Therefore, the correct answer is option B.

The blood component essential for blood coagulation is

  1. Albumin

  2. Globulin

  3. Fibrinogen

  4. Vitamins


Correct Option: C
Explanation:

Coagulation or clotting is a process where the blood in liquid form turns into a gel. The mechanism involves activation, adhesion and aggregation of platelets and deposition of fibrinogen. Though this is an inactive clotting factor, it helps to clot by the formation of insoluble fibrin.

Therefore, the correct answer is option C.

The function of vitamin K is in 

  1. Regulation of calcium and phosphorus metabolism

  2. Blood clotting

  3. Respiration

  4. Carbohydrate metabolism


Correct Option: B
Explanation:
Vitamin K plays an important role in blood clotting. It is required by the body for the synthesis of prothrombin by the liver. Prothrombin is a plasma protein which gets converted into thrombin during the clotting process and thus helps in clotting mechanism. 
Thus, the correct answer is option B. 

Blood clot inside a blood vessel is known as  

  1. Thrombosis

  2. Agglutinin

  3. Clot

  4. Thrombus


Correct Option: D
Explanation:

blood clot that forms inside one of your veins or arteries is called a thrombus. A thrombus may also form in your heart. A thrombus that breaks loose and travels from one location in the body to another is called an embolus.

So, the correct option is 'Thrombus'.

Read the statements given below and choose the correct sequence of events leading the formation of a blood clot.
(i) Calcium activates an enzyme.
(ii) Fibrin binds platelets to form a 'plug'.
(iii) Thrombin converts fibrinogen to fibrin.
(iv) Platelets and damaged cells release an activator.

  1. (i), (ii), (iii), (iv)

  2. (ii), (i), (iii), (iv)

  3. (iii), (iv), (i), (ii)

  4. (iv), (i), (iii), (ii)


Correct Option: D
Explanation:
The process of blood clotting starts with the release of thromboplastin from damaged cells and platelets. Thromboplastin converts plasma protein prothrombin into thrombin in the presence of calcium ions. Thrombin then converts soluble plasma protein fibrinogen into fibrin which binds platelets to form a clot. 
Therefore, the correct answer is option D. 

What happens when a clot occurs in an undamaged blood vessel?

  1. The person would bleed to death.

  2. A scab will form on the skin surface.

  3. Platelets stick to the edges of the cut and to one another, forming a plug.

  4. The flow of blood to tissues beyond the clot may be cut off.


Correct Option: D
Explanation:

When a clot occurs in an undamaged blood vessel, It stops the flow of blood to the rest of the tissue beyond the clot as, the blood can't flow through the clot. It causes paralysis in most of the cases. 

Therefore, the correct answer is option D.

Which enzyme induces lysis of fibrinogen to fibrin during fibrinolysis?

  1. Plasmin

  2. Thrombin

  3. Fibrin

  4. Trypsin


Correct Option: B
Explanation:

Blood-clotting proteins circulate in the blood plasma in an inactive form, poised to participate in blood coagulation upon tissue injury. Blood-clotting proteins generate thrombin, an enzyme that converts fibrinogen to fibrin, and a reaction that leads to the formation of a fibrin clot.

Therefore, the correct answer is option B.

In human, the prothrombin required for blood clotting is produced inside the

  1. Liver

  2. Blood

  3. Bone

  4. Spleen


Correct Option: A
Explanation:

Prothrombin is a coagulation or clotting factor that is needed for the normal clotting of blood. A cascade of biochemical events leads to the formation of the final clot. In this cascade, prothrombin is a precursor to thrombin.
Prothrombin is produced in the liver and is modified in the presence of vitamin K.
Therefore, the correct answer is option A.

The component of blood which prevents its coagulation in the blood vessels is

  1. Haemoglobin

  2. Plasma

  3. Thrombin

  4. Heparin


Correct Option: D
Explanation:
Heparin is considered as the natural anticoagulant of the body which prevents blood clotting in blood vessels. It prevents the formation of thrombin. 
Hence, correct answer is option D. 

Which of the following happens if platelets are absent in blood?

  1. Severe bleeding in case of injury or cuts

  2. Body cannot form clots

  3. Thrombocytopenia

  4. All of the above


Correct Option: D
Explanation:

Platelets are components of blood. They prevent bleeding by activating coagulation mechanisms hence contribute in wound healing. They play an important role in inflammatory and proliferative events. If the platelets are not present in the blood there will be continuous loss of blood by the blood vessels which may prove fatal.