Tag: blood clotting

Questions Related to blood clotting

Protein required for coagulation of blood is

  1. Haemoglobin

  2. Globulin

  3. Fibrinogen

  4. Albumin


Correct Option: C
Explanation:
The mechanism of blood clotting involves the presence of calcium and other clotting factors, Factor X activates an enzyme called prothrombin activator. The enzyme prothrombin activator then converts plasma protein prothrombin into thrombin. Thrombin is the enzyme which in turn converts fibrinogen into fibrin. Polymerized fibrin together with platelets forms a clot at the wound site. Hence Protein required for coagulation of blood is Fibrinogen. It is a blood plasma protein made in the liver and present in circulating blood.
So, the correct answer is 'Fibrinogen'

Enzyme causing lysis of fibrin during fibrinolysis is

  1. Fibrinogen

  2. Plasmin

  3. Thrombin

  4. VIII Platelet factor


Correct Option: B
Explanation:

Fibrinolysis is a process that prevents blood clots from growing and becoming problematic. This process has two types: primary fibrinolysis and secondary fibrinolysis. The primary type is a normal body process, whereas secondary fibrinolysis is the breakdown of clots due to a medicine, a medical disorder, or some other causes. In fibrinolysis, a fibrin clot, the product of coagulation, is broken down. Its main enzyme plasmin cuts the fibrin mesh at various places, leading to the production of circulating fragments that are cleared by other proteases or by the kidney and liver. Hence Enzyme causing lysis of fibrin during fibrinolysis is plasmin.

So, the correct answer is 'Plasmin'.

The coagulation of blood occurs due to

  1. Destruction of erythrocytes.

  2. Destruction of leucocytes.

  3. Change of fibrinogen into fibrin.

  4. Formation of serum.


Correct Option: C
Explanation:
The mechanism of blood clotting involves The presence of calcium and other clotting factors, Factor X activates an enzyme called prothrombin activator. The enzyme prothrombin activator then converts plasma protein prothrombin into thrombin. Thrombin is the enzyme which in turn converts fibrinogen into fibrin. Polymerized fibrin together with platelets forms a clot at the wound site. Hence The coagulation of blood occurs due to change of fibrinogen into fibrin.
So, the correct answer is 'Change of fibrinogen into fibrin'.

Thrombokinase is produced in

  1. RBC

  2. WBC

  3. Blood vessels

  4. Blood clotting


Correct Option: D
Explanation:

Thrombokinase is also known as thromboplastin. It is a complex enzyme which aids in clotting of blood. It is present in platelets and some body tissues. When the platelets aggregate at the site of injury, thrombokinase is released from platelets and damaged tissues. Thrombokinase converts prothrombin into thrombin which acts as an enzyme and converts fibrinogen into fibrin threads. The fibrin threads form a clot at the site of injury. Hence thrombokinase is produced in blood clotting.

So, the correct answer is 'Blood clotting'

During blood coagulation, vitamin K helps in

  1. Formation of prothrombin

  2. Formation of thromoboplastin

  3. Conversion of fibrinogen into fibrin

  4. Conversion of prothrombin to thrombin.


Correct Option: A

Blood protein which initiates blood coagulation is

  1. Prothrombin

  2. Thrombin

  3. Fibrinogen

  4. Fibrin


Correct Option: A
Explanation:
Prothrombin is a plasma protein essential for blood clotting. Whenever there is an injury, prothrombin activator complex is formed. Prothrombin is converted into thrombin by activators. Thrombin acts as an enzyme and converts plasma protein fibrinogen into fibrin threads which form a clot at the site of injury and bleeding is stopped.
So, the correct answer is 'Prothrombin'.

Which one of the following substances, if introduced in blood stream would cause coagulation of blood at the site of its introduction?

  1. Prothrombin

  2. Fibrinogen

  3. Thromboplastin

  4. Heparin.


Correct Option: C

Find the correct explanations about blood not clotting inside the vessels
1. Speedy flow prevents accumulation of fibrin threads if formed
2. Absence of anticoagulant heparin having antithrombin activity
3. Smoothness of endothelial lining preventing rupturing of platelets and formation of thromboplastin
4. Presence of a layer of negetively charged protein over the inner surface of endothelium that attracts clotting factors.

  1. 1, 2, 3 correct

  2. 1, 2 correct

  3. 2, 4 correct

  4. 1, 3 correct.


Correct Option: D

Which one of the following proteins is involved in the coagulation of blood

  1. Globulin

  2. Fibrinogen

  3. Albumin

  4. Serum amylase.


Correct Option: B

In extrinsic clotting pathway, active factor VI activates factors

  1. X and XI

  2. IX and X

  3. IX and XI

  4. XI and XII.


Correct Option: B