Tag: blood clotting

Questions Related to blood clotting

The function of vitamin K is in

  1. Regulation of calcium and phosphorus metabolism

  2. Blood clotting

  3. Respiration

  4. Carbohydrate metabolism


Correct Option: B
Explanation:

Vitamin K plays an important role in blood clotting. It is required by the body for the synthesis of prothrombin by the liver. Prothrombin is a plasma protein which gets converted into thrombin during the clotting process and thus helps in clotting mechanism. Thus, the correct answer is option B. 

An anticoagulant used for preventing clotting in vitro is sodium oxalate. It prevents clot formation by

  1. Combining with cations in the blood

  2. Inhibiting clotting factor VIII activity

  3. Getting itself deposited over the surface of ROC

  4. Blocking the fibrinogen activity


Correct Option: A
Explanation:

Sodium oxalate (like citrates) can be used to remove calcium ions (Ca$^{2+}$) from the blood plasma. The oxalate prevents clotting by forming insoluble calcium salts, thus removing ionic calcium (or cations).
Therefore, the correct answer is option A.

In human, the prothrombin required for blood clotting is produced in

  1. Liver

  2. Stomach

  3. Pancreas

  4. Spleen


Correct Option: A
Explanation:

Prothrombin is a plasma glycoprotein produced in the liver. It gets converted into thrombin by a clotting factor prothrombinase which further transforms fibrinogen into fibrin which combines with platelets to form clot. 

Blood doesn't clot in the absence of vitamin K because it is

  1. An essential component of the clot

  2. An essential component of the platelets

  3. Essential for synthesis of prothrombin

  4. Essential for synthesis of fibrinogen


Correct Option: C
Explanation:

Blood clotting factors are needed for blood to clot (coagulation). Prothrombin, or factor II, is one of the clotting factors made by the liver. Vitamin K is needed to make prothrombin and other clotting factors. So, blood does not clot in the absence of Vitamin K because it is essential for the synthesis of prothrombin and not because it is an essential component of the clot, platelets or essential for fibrinogen. 

Thus, the correct answer is option C. 

Clotting of blood is brought about by

  1. RBCs

  2. WBCs

  3. Platelets

  4. Plasma


Correct Option: C
Explanation:

Platelets are tiny components in blood that initiate blood clots by releasing thromboplastin at the site of injury. Thromboplastin initiates the process of blood clotting. Thus, the correct answer is option C.

Coagulation of blood in vessels is prevented during normal circulation by

  1. Heparin

  2. Prothrombin

  3. Plasminogen

  4. Thromplastin


Correct Option: A
Explanation:

Heparin is a natural anticoagulant of the body produced in the liver. It is normally found circulating through the bloodstream. It prevents the blood clotting in veins and arteries during normal circulation.

Thus, the correct answer is option A.

Haemophilia is a condition where there is 

  1. A failure in the clotting mechanism of blood

  2. A delay in the clotting of blood

  3. No production of haemoglobin in the blood

  4. No production of melanin in the skin


Correct Option: A
Explanation:

  • Haemophilia is a group of hereditary genetic disorders in which the body's blood clotting ability fails to stop bleeding if any cut happens.
  • Thus, it is also known as bleeder's disease. One type of haemophilia called haemophilia A happens due to the deficiency of blood clotting factor VIII. 
Therefore, the correct answer is option A.

Which of the metallic ions is essential for blood clotting?

  1. Na$^+$

  2. Ca$^{++}$

  3. K$^+$

  4. Fe$^{++}$


Correct Option: B
Explanation:
Calcium ions along with vitamin K are essential for clotting process as all the reaction in the clotting process take place in the presence of calcium ions. It is very important for the conversion reaction of prothrombin into the thrombin.
Therefore, the correct answer is option B.

Thrombin occurs in vertebrates in 

  1. The blood and gives it red colour

  2. The blood and is important for clotting

  3. The liver and is important for bile secretion

  4. The stomach and digests proteins


Correct Option: B
Explanation:
Thrombin is a substance formed in one of the steps of clotting process from prothrombin. Thrombin, in turn, converts fibrinogen into fibrin which ultimately forms a clot. 
Thus, the correct answer is option B. 

In human, the prothrombin required for blood clotting is produced in 

  1. Liver

  2. Stomach

  3. Pancreas

  4. Spleen


Correct Option: A
Explanation:

In human, the prothrombin required for blood clotting is produced in the liver in the presence of vitamin K. It gets converted into thrombin in the presence of thromboplastin and thus forms an essential step in the clotting process. 

Therefore, the correct answer is option A.