Tag: blood clotting

Questions Related to blood clotting

Which one functions as enzyme in blood clotting

  1. Prothrombin

  2. Calcium

  3. Thrombin

  4. Fibrin.


Correct Option: C

Identify the correct sequence of blood coagulation (a) Activation of prothrombin (b) Formation of prothrombin activator (c) Formation of blood clot (d) Conversion of fibrinogen to fibrin

  1. b - d - a - c

  2. b - a - d - c

  3. a - d - c - b

  4. a - b - c - d


Correct Option: B
Explanation:
Blood coagulation occurs in the following sequence:
  • Whenever there is rupture of blood vessels or damage is caused to blood, a complex of substances called prothrombin activator complex is formed. 
  • The activators convert prothrombin into thrombin.
  • Thrombin acts as an enzyme and converts fibrinogen into fibrin threads.
  • Fibrin threads accumulate and clump to form blood clot at the wound site.
So, the correct answer is 'b- a- d- c'.

The factor which initiates intrinsic pathway of blood clotting and triggers cascade reaction is

  1. Antihaemophiliac factor (VIII)

  2. Christmas factor (IX)

  3. Stuart-Prower factor (X)

  4. Hageman's factor (XII).


Correct Option: D

Thrombokinase is associated with

  1. Elimination of area and other excretory products from the body

  2. Production of erythrocytes from the bone marrow

  3. Pulmonary and systemic circulation

  4. Cardiac cycle and its regulation

  5. Enzymatic reactions in coagulation of blood.


Correct Option: E

Thrombokinase is associated with

  1. Ellimination of urea and other excreatory products from the body.

  2. Production of erythrocytes from the bone marrow.

  3. Pulmonary and systematic circulation.

  4. Cardiac cycle and its regulation

  5. Enzymatic reactions in coagulation of blood.


Correct Option: E
Explanation:

Thrombokinase is a substance present in platelets which are necessary for coagulation of blood. Thromboplastin helps in the conversion of prothrombin to thrombin in the presence of calcium which is the vital step in coagulation of blood.

Hence, the correct option is E.

Which one has no clotting property?

  1. Blood

  2. Lymph

  3. Tissue fluid

  4. None of the above.


Correct Option: A

Blood agglutination tests are used in

  1. Antigen antibody reaction

  2. Animal relations

  3. Immunity

  4. None of the above


Correct Option: A
Explanation:
Blood agglutination tests are used in Antigen-antibody reactions. The clumping of particles is called as agglutination. Clumping occurs when an antigen is mixed with its corresponding antibody. When people are given blood transfusions of the wrong blood group, the antibodies react with the incorrectly transfused blood group and as a result, the erythrocytes clump up and stick together causing them to agglutinate 
So, the correct answer is 'Antigen-antibody reaction'.

Blood precipitation test was proposed by

  1. Wallace

  2. Nuttal

  3. Bateson

  4. Needham


Correct Option: A
Explanation:
Blood precipitation test was proposed by Wallace. Blood precipitation reactions are based on the interaction between antibodies and antigens. They are based on two soluble reactants (Antigen and antibody) that come together to make one insoluble product(Antigen-Antibody complex), the precipitate. 
So, the correct answer is 'Wallace'.

Conversion of fibrinogen to fibrin is catalysed by

  1. Thrombin

  2. Prothrombin

  3. Thromboplastin

  4. All of these


Correct Option: A
Explanation:
Thrombin catalyzes the conversion of fibrinogen (factor I)—a soluble plasma protein into long, sticky threads of insoluble fibrin . The fibrin threads form a mesh that traps platelets, blood cells, and plasma.The fibrin mesh work begins to contract in a short period of time and prevents blood loss. 
So, the correct answer is 'Thrombin'

During the process of blood coagulation, vitamin k helps in

  1. The formation of thromboplastin

  2. The conversion of fibrinogen to fibrin

  3. The conversion of prothrombin to thrombin

  4. The formation of prothrombin


Correct Option: D
Explanation:

Vitamin K helps in the synthesis of prothrombin in the liver.

So, the correct answer is 'The formation of prothrombin'